Adenoid Variant of Basal Cell Carcinoma: A Case Report with a Glance at Biological Behavior of the Tumor

are the frequently reported side effects, adverse cutaneous reactions are extremely rare. There are a few reports of acute generalized exanthematous pustulosis caused by faropenem and meropenem. However, bullous skin eruptions have not been reported, yet the various types of bullous drug reactions are bullous fixed drug reactions (FDRs), Stevens–Johnson syndrome and toxic epidermal necrolysis, drug-induced autoimmune vesiculobullous disorders, pseudoporphyria, and drug-induced coma blisters. [4] There are isolated reports of cell poor subepidermal blistering due to fluvoxamine, e-aminocaproic acid, and sibutramine. The closest differential diagnoses in this case were bullous FDR and drug-induced bullous pemphigoid. The histopathological features were not conforming to that of FDR where necrotic keratinocytes are numerous with prominent interface dermatitis and plenty of melanophages in the upper dermis. [6] Moreover, a minimal postinflammatory hyperpigmentation in this patient when seen on subsequent follow-up was not in favor of a diagnosis of bullous FDR. A negative DIF result ruled out the possibility of bullous pemphigoid. Thus, faropenem, a novel broad spectrum antibiotic which is widely used nowadays by physicians, can give rise to adverse cutaneous drug reactions such as generalized bullous eruptions as was reported in our case. The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. There are no conflicts of interest. References 1. Dalhoff A, Nasu T, Okamoto K. Target affinities of faropenem to and its impact on the morphology of gram-positive and gram-negative bacteria. et al. Acute generalized exanthematous pustulosis caused by Faropenem: A possible pathogenetic role for interleukin-23. This is an open access article distributed under the terms of the Creative Commons Attribution‑NonCommercial‑ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non‑commercially, as long as the author is credited and the new creations are licensed under the identical terms. Generalized bullous drug eruption to faropenem ‑ hitherto unreported. Sir, Basal cell carcinomas (BCCs) are the most common cutaneous tumors in western literature, accounting for approximately 70% of all malignant diseases of the skin. [1] BCC as a pronounced fact is a tumor which possess a wide morphological and histopathological spectra. [2] Histological diagnosis and classifying BCCs into …